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IRF1 Antikörper

IRF1 Reaktivität: Human WB Wirt: Maus Monoclonal 13H3A44 unconjugated
Produktnummer ABIN2666257
  • Target Alle IRF1 Antikörper anzeigen
    IRF1 (Interferon Regulatory Factor 1 (IRF1))
    Reaktivität
    • 86
    • 48
    • 34
    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    Human
    Wirt
    • 90
    • 6
    • 1
    • 1
    Maus
    Klonalität
    • 84
    • 14
    Monoklonal
    Konjugat
    • 47
    • 12
    • 9
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IRF1 Antikörper ist unkonjugiert
    Applikation
    • 86
    • 33
    • 14
    • 12
    • 9
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    Affinity purified.
    Klon
    13H3A44
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product IRF1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Upon receipt, store undiluted at 4°C.
  • Target
    IRF1 (Interferon Regulatory Factor 1 (IRF1))
    Andere Bezeichnung
    IRF1 (IRF1 Produkte)
    Synonyme
    irf1 antikoerper, zgc:136945 antikoerper, IRF1 antikoerper, irf11 antikoerper, zgc:103566 antikoerper, IRF-1 antikoerper, MAR antikoerper, AU020929 antikoerper, Irf-1 antikoerper, interferon regulatory factor 1 antikoerper, interferon regulatory factor 1a antikoerper, interferon regulatory factor 1b antikoerper, IRF1 antikoerper, irf1a antikoerper, irf1b antikoerper, Irf1 antikoerper
    Hintergrund
    IRF1 is the first identified member of the interferon regulatory transcription factor family. Its expression is induced in response to pathogen infection or the stimulation of several cytokines, including type I and II IFN, IL-1, IL-6, and TNF-α. Upon stimulation, IRF1 is transcriptionally activated by STAT1 and NFκB transcription factors via the GAS (interferon-gamma-activated sequence) element in the IRF1 promoter. IRF1 plays important roles in mediating immune response during infection and development of T cells and NK cells. In addition to the immunomodulatory functions, IRF1 has also shown to be involved in the regulation of cell cycle progression, tumor suppression, and apoptosis. IRF1-mediated transcription can be repressed by IRF2 through competing for the same binding region on the promoters.
    Pathways
    Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagie
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