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IL-21 Antikörper (Biotin)

IL21 Reaktivität: Human, Maus ICFC Wirt: Maus Monoclonal 7H20-I19-M3 Biotin
Produktnummer ABIN2666224
  • Target Alle IL-21 (IL21) Antikörper anzeigen
    IL-21 (IL21) (Interleukin 21 (IL21))
    Reaktivität
    • 88
    • 30
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 68
    • 23
    • 5
    • 4
    • 1
    Maus
    Klonalität
    • 80
    • 21
    Monoklonal
    Konjugat
    • 53
    • 12
    • 8
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL-21 Antikörper ist konjugiert mit Biotin
    Applikation
    • 69
    • 57
    • 13
    • 12
    • 9
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Intracellular Flow Cytometry (ICFC)
    Kreuzreaktivität (Details)
    Mouse* - weak affinity
    Aufreinigung
    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
    Klon
    7H20-I19-M3
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product IL21 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide. Final antibody concentration is 0.5 mg/mL.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Upon receipt, store frozen between 2°C and 8°C.
  • Target
    IL-21 (IL21) (Interleukin 21 (IL21))
    Andere Bezeichnung
    IL-21 (IL21 Produkte)
    Synonyme
    IL-21 antikoerper, Za11 antikoerper, interleukin 21 antikoerper, IL21 antikoerper, Il21 antikoerper
    Hintergrund
    Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Recent studies have shown that IL-21 is also an autocrine cytokine that potently induces T(H)17 differentiation and suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.
    Pathways
    JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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