IFNAR1 Antikörper

Produktnummer ABIN2666005

Der Maus Monoklonal anti-IFNAR1 Antikörper wird verwendet zum Nachweis von IFNAR1 in Proben von Maus. Er wurde validiert für FACS.

Kurzübersicht für IFNAR1 Antikörper (ABIN2666005)

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IFNAR1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: MAR1-5A3

Produktdetails anti-IFNAR1 Antikörper

Produktmerkmale: This product is produced with low endotoxin and is supplied azide free.

Aufreinigung: The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau:

Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Konservierungsmittel: Azide free

Handhabung: This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu IFNAR1

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Andere Bezeichnung: IFNAR-1

Hintergrund: IFNAR-1, the type I IFN receptor subunit 1, is coexpressed with IFNAR-2 on nearly all cells and make up the heterodimeric receptor complex that binds to all type I IFNs (IFN-α/β). Type I IFNs are a group of structurally and functionally related cytokines that have been shown to promote anti-viral, anti-microbial, anti-tumor, and autoimmune responses. Ligand binding to the IFN-α/β receptor complex leads to the tyrosine phosphorylation and activation of IFNAR-1-associated Tyk2 and IFNAR-2-associated Jak1 signal transductions.

Pathways: JAK-STAT Signalweg, Hepatitis C