IFNAR1 Antikörper
Kurzübersicht für IFNAR1 Antikörper (ABIN2666006)
Target
Alle IFNAR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Marke
- Ultra-LEAF™
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Aufreinigung
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
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Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
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Isotyp
- IgG1 kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Konservierungsmittel
- Azide free
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Handhabung
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
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Lagerung
- 4 °C
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Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
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Andere Bezeichnung
- IFNAR-1
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Hintergrund
- IFNAR-1, the type I IFN receptor subunit 1, is coexpressed with IFNAR-2 on nearly all cells and make up the heterodimeric receptor complex that binds to all type I IFNs (IFN-α/β). Type I IFNs are a group of structurally and functionally related cytokines that have been shown to promote anti-viral, anti-microbial, anti-tumor, and autoimmune responses. Ligand binding to the IFN-α/β receptor complex leads to the tyrosine phosphorylation and activation of IFNAR-1-associated Tyk2 and IFNAR-2-associated Jak1 signal transductions.
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Pathways
- JAK-STAT Signalweg, Hepatitis C
Target
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