XBP-1s Antikörper

Produktnummer ABIN2665459

Der Maus Monoklonal anti-XBP-1s Antikörper wird verwendet zum Nachweis von XBP-1s in Proben von Human und Maus. Er wurde validiert für WB.

Kurzübersicht für XBP-1s Antikörper (ABIN2665459)

Target: XBP-1s

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Klon: 9D11A43

Produktdetails

Kreuzreaktivität: Human

Aufreinigung: The antibody was purified by affinity chromatography.

Isotyp: IgG2a kappa, IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Antigendetails

Target: XBP-1s

Hintergrund: XBP-1 is a transcription factor containing a bZIP domain. It was first identified because of its ability to bind X-box, a conserved transcriptional element in the promoter of the human HLA-DR gene. XBP-1 has multiple functions. It controls MHC class II gene regulation and is also essential for differentiation of plasma cells. XBP-1 is upregulated as part of the ER stress response, also known as the unfolded protein response.