Oct-2 Antikörper

Produktnummer ABIN2665310

Dieses Anti-Oct-2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Oct-2 in FACS. Geeignet für Human und Maus.

Kurzübersicht für Oct-2 Antikörper (ABIN2665310)

Target: Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Oct-2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 2B10B19

Produktdetails anti-Oct-2 Antikörper

Kreuzreaktivität: Maus

Aufreinigung: The antibody was purified by affinity chromatography.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu Oct-2

Target: Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))

Andere Bezeichnung: Oct-2

Hintergrund: OCT2 is a member of the POU family of transcription factors that was found to be expressed predominantly in B lymphocytes, activated T lymphocytes, and neuronal cells. OCT2 binds to the conserved octamer DNA element, ATGCAAAT, which was discovered in the promoters and enhancers of immunoglobulin (Ig) genes. In addition to regulating Ig gene expression, OCT2 controls several B cell specific genes required for proliferation and differentiation, such as CD20, CD36, and CD79a. OCT2 was found to have different isoforms produced by alternative splicing. The OCT2 isoforms exert distinct functional activities and can act as transcriptional activators or repressors.