LTBR Antikörper

Produktnummer ABIN2665249

Der Ratte Monoklonal anti-LTBR Antikörper wird verwendet zum Nachweis von LTBR in Proben von Maus. Er wurde validiert für FACS und IHC.

Kurzübersicht für LTBR Antikörper (ABIN2665249)

Target: LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser LTBR Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC)

Klon: 5G11

Produktdetails anti-LTBR Antikörper

Aufreinigung: The antibody was purified by affinity chromatography.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu LTBR

Target: LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

Andere Bezeichnung: Lymphotoxin beta Receptor

Hintergrund: LTβR is a type I transmembrane glycoprotein and member of the TNF receptor superfamily. It is a 61 KDa receptor for the mouse LTα1β2 and LIGHT. Northern blot analysis of tissues from adult mice showed that expression levels of LTβ R mRNA were strong in lung, liver, and kidney, moderate in heart and testes, but weak in brain, thymus, spleen, and lymph nodes. It was reported that LTβR is expressed on stromal cells, monocytes, and certain embryonic epithelial layers. LTβR is involved in peripheral lymphoid tissue organogenesis and function. The LTα/LTβR receptor system may also have some function in early embryogenesis.

Pathways: NF-kappaB Signalweg