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EPO Antikörper

EPO Reaktivität: Maus FACS Wirt: Ratte Monoclonal M029F6 unconjugated
Produktnummer ABIN2664956
  • Target Alle EPO Antikörper anzeigen
    EPO (Erythropoietin (EPO))
    Reaktivität
    • 123
    • 31
    • 23
    • 7
    • 6
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 107
    • 49
    • 2
    • 1
    • 1
    Ratte
    Klonalität
    • 109
    • 51
    Monoklonal
    Konjugat
    • 89
    • 17
    • 13
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EPO Antikörper ist unkonjugiert
    Applikation
    • 116
    • 73
    • 48
    • 41
    • 29
    • 14
    • 14
    • 13
    • 13
    • 13
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Aufreinigung
    The antibody was purified by affinity chromatography.
    Klon
    M029F6
    Isotyp
    IgG2b
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  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    EPO (Erythropoietin (EPO))
    Andere Bezeichnung
    EPO (EPO Produkte)
    Synonyme
    EPO antikoerper, EP antikoerper, MVCD2 antikoerper, erythropoietin antikoerper, erythropoietin S homeolog antikoerper, erythropoietin a antikoerper, EPO antikoerper, epo antikoerper, epo.S antikoerper, Epo antikoerper, epoa antikoerper
    Substanzklasse
    Hormone
    Hintergrund
    EPO is a glycoprotein that is glycosylated up to 40-60 % , which causes its molecular weight to vary from 30-34 kD depending on the carbohydrate percentage. Hypoxia induces erythropoiesis, and hypoxia inducible factor (HIF) is directly involved in EPO expression. HIF-Prolyl hydroxylase (HIF-PH) is a sensor of levels of iron, oxygen, and metabolic activity. High levels of HIF protein induces EPO production in the kidneys and liver, and mobilizes iron to support erythropoiesis. EPO has been used in the treatment of anemia associated with chronic kidney disease, treatment of cancer patients on chemotherapy, and antiviral HIV therapy.
    Pathways
    JAK-STAT Signalweg, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
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