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EPO Antikörper

EPO Reaktivität: Human FACS Wirt: Maus Monoclonal M0312E3 unconjugated
Produktnummer ABIN2664955
  • Target Alle EPO Antikörper anzeigen
    EPO (Erythropoietin (EPO))
    Reaktivität
    • 122
    • 31
    • 24
    • 7
    • 6
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 107
    • 48
    • 2
    • 2
    • 1
    Maus
    Klonalität
    • 109
    • 51
    Monoklonal
    Konjugat
    • 89
    • 17
    • 13
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EPO Antikörper ist unkonjugiert
    Applikation
    • 116
    • 73
    • 48
    • 41
    • 29
    • 14
    • 14
    • 13
    • 13
    • 13
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Aufreinigung
    The antibody was purified by affinity chromatography.
    Klon
    M0312E3
    Isotyp
    IgG2b kappa
    Top Product
    Discover our top product EPO Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    EPO (Erythropoietin (EPO))
    Andere Bezeichnung
    EPO (EPO Produkte)
    Synonyme
    EPO antikoerper, EP antikoerper, MVCD2 antikoerper, erythropoietin antikoerper, erythropoietin S homeolog antikoerper, erythropoietin a antikoerper, EPO antikoerper, epo antikoerper, epo.S antikoerper, Epo antikoerper, epoa antikoerper
    Substanzklasse
    Hormone
    Hintergrund
    EPO is the major regulator of differentiation, proliferation, and survival of erythroid progenitors. Hypoxia induces erythropoiesis which causes cells to produce hypoxia inducible factor (HIF) that is directly involved in EPO expression. HIF-Prolyl hydroxylase (HIF-PH) is a sensor of levels of iron, oxygen, and metabolic activity. High levels of HIF protein induce EPO production in the kidneys and liver, and mobilize iron to support erythropoiesis. EPO has been used in the treatment of anemia associated with a number of conditions, such as chronic kidney disease, cancer patients on chemotherapy, and antiviral HIV therapy.
    Pathways
    JAK-STAT Signalweg, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
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