DDX17 Antikörper

Produktnummer ABIN2664924

Produktdetails anti-DDX17 Antikörper

Target: DDX17 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 17 (DDX17))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DDX17 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Aufreinigung: The antibody was purified by affinity chromatography.

Klon: 1B5B09

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu DDX17

Target: DDX17 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 17 (DDX17))

Andere Bezeichnung: DDX17 (DDX17 Produkte)

Synonyme: MGC80019 antikoerper, DDX17 antikoerper, P72 antikoerper, RH70 antikoerper, Cp68 antikoerper, DDX46 antikoerper, 2610007K22Rik antikoerper, A430025E01Rik antikoerper, AI047725 antikoerper, C80929 antikoerper, Gm926 antikoerper, p72 antikoerper, DEAD-box helicase 17 L homeolog antikoerper, probable ATP-dependent RNA helicase DDX17 antikoerper, DEAD-box helicase 17 antikoerper, DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 antikoerper, ddx17.L antikoerper, LOC412313 antikoerper, DDX17 antikoerper, ddx17 antikoerper, Ddx17 antikoerper

Hintergrund: DDX17 is an ATP-dependent RNA helicase, belonging to the DEAD (Asp-Glu-Ala-Asp) box superfamily and highly related to the other key family member DDX5. The RNA helicase activity of DDX17 has been implicated in the regulation of RNA metabolism, such as RNA splicing, RNA editing, RNA degradation, and modulating secondary RNA structure. DDX17 can act as a transcriptional co-activator for the estrogen receptor ERα. It is also involved in muscle cell differentiation by co-activating MyoD. DDX17 regulates histone modification through interacting with the acetyltransferases p300, CBP, and PCAF, and the histone deacetylase HDAC1. DDX17 deficient mice exhibit severe developmental problems and die shortly after birth.

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Muscle Cell Differentiation