DDX17 Antikörper (C-Term)

Produktnummer ABIN7448513

Der Kaninchen Polyklonal anti-DDX17 Antikörper wird verwendet zum Nachweis von DDX17 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für DDX17 Antikörper (C-Term) (ABIN7448513)

Target: DDX17 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 17 (DDX17))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDX17 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-DDX17 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Rabbit anti-DDX17 IHC Antibody, Affinity Purified

Homologie: Dog,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Crab-eating macaque,Little brown bat,Northern white-cheeked gibbon

Aufreinigung: Affinity Purified

Immunogen: Between AA 550 and C-term

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1:100 - 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu DDX17

Target: DDX17 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 17 (DDX17))

Andere Bezeichnung: DDX17

Hintergrund: Background: DDX17 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. Some members of the DEAD box proteins also exhibit functions involved in transcriptional regulation. In addition to a role involved in RNA splicing, DDX17 has been observed to interact with and act as a transcriptional coactivator for estrogen receptor alpha (ERalpha). DDX17 is closely related to and forms heterodimers with DDX5.

Gen-ID: 10521

UniProt: Q92841

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Muscle Cell Differentiation