PLAUR Antikörper

Produktnummer ABIN2664853

Der Maus Monoklonal Anti-PLAUR-Antikörper wurde für FACS validiert. Er ist geeignet, PLAUR in Proben von Human zu detektieren.

Kurzübersicht für PLAUR Antikörper (ABIN2664853)

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PLAUR Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: VIM5

Produktdetails anti-PLAUR Antikörper

Aufreinigung: The antibody was purified by affinity chromatography.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu PLAUR

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Andere Bezeichnung: CD87

Hintergrund: CD87, known as urokinase plasminogen activator-receptor (uPAR), is a 36-68 kD single-chain glycophosphotidylinositol (GPI)-anchored glycoprotein. The extracellular region of CD87 consists of three homologous domains, D1, D2, and D3. Membrane-bound and soluble (D2D3) forms of uPAR have been reported. The membrane-bound CD87 is expressed on granulocytes, monocytes/macrophages, dendritic cells, fibroblasts, endothelial cells and keratinocytes. CD87 plays a role in cell adhesion and chemotaxis through binding to β1, β2 and β3 integrins. CD87-bound uPA converts plasminogen to plasmin.

Pathways: Inositol Metabolic Process