Der Ratte Monoklonal anti-CD31 Antikörper (Klon 390) (ABIN2664553) detektiert spezifisch CD31 in FACS, IHC und IF.
Dieser Antikörper reagiert spezifisch mit Proben aus Maus.
CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1) and EndoCAM. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (αv β3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation and angiogenesis.