RANKL Antikörper
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- Target Alle RANKL (TNFSF11) Antikörper anzeigen
- RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser RANKL Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Aufreinigung
- The antibody was purified by affinity chromatography.
- Klon
- MIH24
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product TNFSF11 Primärantikörper
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 221-300) antibody
TNFSF11 Reaktivität: Human, Maus, Ratte, Kaninchen WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 74-308) antibodyTNFSF11 Reaktivität: Human WB, ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 8A7B9 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (C-Term) antibodyTNFSF11 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 210-317) antibodyTNFSF11 Reaktivität: Human, Maus, Ratte, Kaninchen WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 78-317) antibodyTNFSF11 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 92-263) antibodyTNFSF11 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 106-240) antibodyTNFSF11 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 1-30) antibodyTNFSF11 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 73-306) antibodyTNFSF11 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 1-30), (N-Term) antibodyTNFSF11 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB21817 unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
- Andere Bezeichnung
- CD254 (TNFSF11 Produkte)
- Hintergrund
- Human CD254, also known as RANKL, TRANCE, and OPGL, is a type II transmembrane protein in the TNF superfamily that has two forms: a membrane-anchored protein and a secreted protein. Its extracellular domain is related to TRAIL, FasL, and TNF. CD254 is expressed on osteoclasts and activated T cells. It has been implicated in the regulation of the interactions between T cells and dendritic cells. It plays an important role in osteoclast differentiation and bone resorption. CD254 activates JNK and NF-κB and induces the expression of IL-1, IL-6, IL-12, and IL-15 in dendritic cells.
- Pathways
- NF-kappaB Signalweg
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