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TEK Antikörper

TEK Reaktivität: Maus ELISA, FACS, IF Wirt: Ratte Monoclonal TEK4 unconjugated
Produktnummer ABIN2664376
  • Target Alle TEK Antikörper anzeigen
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    Reaktivität
    • 134
    • 70
    • 46
    • 21
    • 3
    • 3
    Maus
    Wirt
    • 117
    • 28
    • 7
    • 3
    • 2
    Ratte
    Klonalität
    • 123
    • 34
    Monoklonal
    Konjugat
    • 75
    • 12
    • 8
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TEK Antikörper ist unkonjugiert
    Applikation
    • 79
    • 58
    • 40
    • 40
    • 36
    • 33
    • 13
    • 13
    • 13
    • 8
    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)
    Aufreinigung
    The antibody was purified by affinity chromatography.
    Klon
    TEK4
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product TEK Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Phosphate buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    Andere Bezeichnung
    CD202b (TEK Produkte)
    Hintergrund
    CD202b, also known as Tie-2 or TEK, is a 145 kD type I transmembrane protein. It is a member of the receptor tyrosine kinase (RTK) family of proteins and is expressed by endothelial cells and their progenitors, quiescent hematopoietic stem cells (HSCs), and a subpopulation of monocytes. Angiopoietin-1 (Ang-1) is an activator of CD202b to promote, maintain, and stabilize mature vessels and to maintain HSCs in the quiescent state. Ang-2 is another ligand of CD202b, which is involved in postnatal angiogenesis and in antagonizing the effects of Ang-1. Tie-2 also binds to Ang-4.
    Pathways
    RTK Signalweg, Growth Factor Binding
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