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PDGFRA Antikörper

PDGFRA Reaktivität: Maus FACS Wirt: Ratte Monoclonal APA5 unconjugated
Produktnummer ABIN2664222
  • Target Alle PDGFRA Antikörper anzeigen
    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
    Reaktivität
    • 227
    • 108
    • 62
    • 20
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 194
    • 43
    • 7
    • 1
    Ratte
    Klonalität
    • 186
    • 59
    Monoklonal
    Konjugat
    • 113
    • 17
    • 17
    • 15
    • 13
    • 12
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PDGFRA Antikörper ist unkonjugiert
    Applikation
    • 164
    • 102
    • 64
    • 54
    • 54
    • 47
    • 37
    • 25
    • 22
    • 14
    • 9
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Aufreinigung
    The antibody was purified by affinity chromatography.
    Klon
    APA5
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product PDGFRA Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
    Andere Bezeichnung
    CD140a (PDGFRA Produkte)
    Hintergrund
    Platelet-derived growth factor receptor-α (PDGFR-α), CD140a, is one of two receptors for platelet-derived growth factors (PDGFs) and binds to all isoforms of PDGFs: PDGF-AA, PDGF-AB, and PDGF-BB. PDGFRa is a receptor tyrosine kinase that forms homodimers or heterodimers on the surface upon ligand binding and phosphorylates substrates. PDGFRs consist of either homodimers of α/α, β/β, or heterodimers of α/β. PDGF receptors, α and β, are single glycoproteins with intracellular tyrosine kinase domain. Their ligand, PDGF, is a mitogen for connective tissue and glial cells. CD140a is expressed on embryonic tissues and mesenchymal-derived cells of adult mice. PDGF plays a role in wound healing and acts as a chemoattractant for fibroblasts, smooth muscle cells, glial cells, monocytes, and neutrophils.
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Platelet-derived growth Factor Receptor Signaling
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