CCR8 Antikörper

Produktnummer ABIN2664101

Dieses Anti-CCR8-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CCR8 in IHC, ELISA (Capture), ELISPOT (Capture) und ICFC. Geeignet für Human.

Kurzübersicht für CCR8 Antikörper (ABIN2664101)

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CCR8 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA (Capture), ELISpot (Capture) (ELISPOT (Capture)), Intracellular Flow Cytometry (ICFC)

Klon: L263G8

Produktdetails anti-CCR8 Antikörper

Aufreinigung: The antibody was purified by affinity chromatography.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu CCR8

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Andere Bezeichnung: CCR8

Hintergrund: CCR8, also known as ChemR1, TER1, and CKR-L1, belongs to the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. CCR8 is expressed on some subsets of T cells, monocytes, macrophages, eosinophils, thymocytes, Langerhans cells, neurons, and vascular smooth muscle cells. Binding with its ligand CCL1, CCR8 plays a role in the regulation of monocyte chemotaxis and thymic cell apoptosis. It has been reported that CCR8 is also a receptor for CCL18. CCR8 is also believed to be an alternative coreceptor to CD4 for HIV-1 infection.