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Caspase 4 Antikörper

CASP4 Reaktivität: Maus FACS Wirt: Ratte Monoclonal Cas11-17D9 unconjugated
Produktnummer ABIN2664092
  • Target Alle Caspase 4 (CASP4) Antikörper anzeigen
    Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
    Reaktivität
    • 59
    • 33
    • 15
    • 14
    • 1
    Maus
    Wirt
    • 78
    • 11
    • 1
    • 1
    • 1
    Ratte
    Klonalität
    • 77
    • 14
    Monoklonal
    Konjugat
    • 54
    • 15
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser Caspase 4 Antikörper ist unkonjugiert
    Applikation
    • 75
    • 29
    • 27
    • 12
    • 9
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    Flow Cytometry (FACS)
    Aufreinigung
    The antibody was purified by affinity chromatography.
    Klon
    Cas11-17D9
    Isotyp
    IgG2a
    Top Product
    Discover our top product CASP4 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
    Andere Bezeichnung
    Caspase-11 (CASP4 Produkte)
    Synonyme
    ICE(rel)II antikoerper, ICEREL-II antikoerper, ICH-2 antikoerper, Mih1/TX antikoerper, TX antikoerper, Casp11 antikoerper, CASP13 antikoerper, CASP1 antikoerper, CASP4 antikoerper, Caspl antikoerper, ich-3 antikoerper, Casp4 antikoerper, caspase 4 antikoerper, caspase 4, apoptosis-related cysteine peptidase antikoerper, caspase-4 antikoerper, CASP4 antikoerper, Casp4 antikoerper, LOC100731032 antikoerper
    Hintergrund
    Murine caspase-11 is an upstream protease of caspase-1 and interacts with the proform of caspase-1 which in turn activates IL-1 beta. Caspase-11 is not constitutively expressed in most cell types. Its expression can be upregulated by LPS, IFN-gamma, and other pro-inflammatory stimuli. NF-κB and STAT1 were reported to be involved in the activation. Caspase-11 knock -out mice were resistant to endotoxin shock and do not produce IL-1 after stimulation with LPS. Their production of IFN-gamma was also deficient.
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
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