C3AR1 Antikörper

Produktnummer ABIN2664086

Der Maus Monoklonal anti-C3AR1 Antikörper (Klon hC3aRZ8) (ABIN2664086) detektiert spezifisch C3AR1 in FACS und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für C3AR1 Antikörper (ABIN2664086)

Target: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser C3AR1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC)

Klon: HC3aRZ8

Produktdetails anti-C3AR1 Antikörper

Aufreinigung: The antibody was purified by affinity chromatography.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu C3AR1

Target: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Andere Bezeichnung: C3AR

Hintergrund: C3AR is a single chain protein of 482 aa, with seven membrane-spanning regions and a molecular weight of 54 Kd. C3AR is expressed by neutrophils, eosinophils, mast cells, monocytes, dendritic cells and there are reports of C3AR expression in non-immune cells such as hematopoietic and mesenchymal stem cells, epithelial and endothelial cells. C3AR is coupled to heterotrimeric G proteins and after C3a binding, the signal transduced, results in chemotaxis, granule enzyme release and superoxide anion production.

Pathways: Komplementsystem