CEBPA Antikörper
Kurzübersicht für CEBPA Antikörper (ABIN2664083)
Target
Alle CEBPA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Kreuzreaktivität
- Maus
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Kreuzreaktivität (Details)
- weakly cross-reacts with mouse
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Aufreinigung
- The antibody was purified by affinity chromatography.
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Isotyp
- IgG2a kappa
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anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) antibody
CEBPA Reaktivität: Human WB, ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 5B7 unconjugated
anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) antibodyCEBPA Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, FACS, IF/ICC Wirt: Maus Monoclonal unconjugated
anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (AA 1-205) antibodyCEBPA Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (pSer21) antibodyCEBPA Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (pThr226) antibodyCEBPA Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (AA 288-337) antibodyCEBPA Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Schwein, Hund, Kaninchen, Huhn WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (N-Term) antibodyKO Validated CEBPA Reaktivität: Human WB, IHC (p), IP, ChIP Wirt: Kaninchen Polyclonal unconjugated
anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (N-Term) antibodyCEBPA Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (Middle Region) antibodyCEBPA Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen, Hund, Kaninchen, Pferd, Schaf WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) antibodyCEBPA Reaktivität: Human WB, FACS, EIA Wirt: Maus Monoclonal 4-00E-010 unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))
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Andere Bezeichnung
- C/EBPalpha
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Hintergrund
- The CCAAT-enhancer binding proteins (C/EBP) are members of the basic region/leucine zipper (bZIP) transcription factors, that bind to the consensus CCAAT sequence in DNA. C/EBPα is expressed in two isoforms: p42 and p30 by ultilizing different translational start codons. The C/EBPα p30 isoform has little to no transactivating activity and acts as an inhibitor. C/EBPα regulates expression of various myeloid-specific genes and is required for myeloid differentiation. C/EBPα has been found to play a key role in adipogenesis, since inhibition of C/EBPα blocks adipocyte differentiation. C/EBPα also regulates cell cycle progression through interactions with cyclin-dependent kinases (CDK) and by inducing the expression of CDK inhibitor p21. Mutations in the C/EBPα gene are associated with the development of acute myeloid leukemia.
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Pathways
- Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
Target
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