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IL-21 Antikörper (PE)

IL21 Reaktivität: Human FACS Wirt: Maus Monoclonal 3A3-N2 PE
Produktnummer ABIN2663779
  • Target Alle IL-21 (IL21) Antikörper anzeigen
    IL-21 (IL21) (Interleukin 21 (IL21))
    Reaktivität
    • 89
    • 31
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 68
    • 24
    • 5
    • 4
    • 1
    Maus
    Klonalität
    • 80
    • 22
    Monoklonal
    Konjugat
    • 53
    • 13
    • 8
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL-21 Antikörper ist konjugiert mit PE
    Applikation
    • 69
    • 57
    • 13
    • 12
    • 9
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Flow Cytometry (FACS)
    Kreuzreaktivität
    Rhesusaffen
    Aufreinigung
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    Klon
    3A3-N2
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product IL21 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Protect from prolonged exposure to light. Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    IL-21 (IL21) (Interleukin 21 (IL21))
    Andere Bezeichnung
    IL-21 (IL21 Produkte)
    Synonyme
    IL-21 antikoerper, Za11 antikoerper, interleukin 21 antikoerper, IL21 antikoerper, Il21 antikoerper
    Hintergrund
    Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation, suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.
    Pathways
    JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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