CD180 Antikörper (PE)
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- Target Alle CD180 Antikörper anzeigen
- CD180 (CD180 Molecule (CD180))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD180 Antikörper ist konjugiert mit PE
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Kreuzreaktivität
- Pavian, Cynomolgus, Rhesusaffen
- Aufreinigung
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
- Klon
- MHR73-11
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CD180 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from prolonged exposure to light. Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- CD180 (CD180 Molecule (CD180))
- Andere Bezeichnung
- CD180 (CD180 Produkte)
- Synonyme
- Ly78 antikoerper, CD180 antikoerper, LY64 antikoerper, RP105 antikoerper, F630107B15 antikoerper, CD180 molecule antikoerper, CD180 antigen antikoerper, Cd180 antikoerper, CD180 antikoerper
- Hintergrund
- CD180, also known as RP105, is a 105 kD member of the toll-like receptor (TLR) family and is expressed on most B cells, monocytes/macrophages and dendritic cells. The TLR family's structural characteristics are critically involved in protein-protein signaling interactions leading to the activation of the innate immune system. Additionally, MD-1, a secretory protein, associates with CD180 (RP105) at the cell surface and this complex, in conjunction with TLR4, recognizes bacterial LPS. The human CD180 (RP105) gene maps to 5q12. The MHR73-11 antibody is able to activate B cells and to protect against irradiation- or dexamethasone-induced apoptosis.
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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