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CCRL1 Antikörper (PE)

Dieses Anti-CCRL1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CCRL1 in FACS. Geeignet für Human.
Produktnummer ABIN2662412

Kurzübersicht für CCRL1 Antikörper (PE) (ABIN2662412)

Target

Alle CCRL1 Antikörper anzeigen
CCRL1 (Chemokine (C-C Motif) Receptor-Like 1 (CCRL1))

Reaktivität

  • 19
  • 10
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 16
  • 2
  • 1
Maus

Klonalität

  • 18
  • 1
Monoklonal

Konjugat

  • 19
Dieser CCRL1 Antikörper ist konjugiert mit PE

Applikation

  • 14
  • 11
  • 8
  • 5
  • 5
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Klon

13E11
  • Aufreinigung

    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

    Isotyp

    IgG2b kappa
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Protect from prolonged exposure to light. Do not freeze.

    Lagerung

    4 °C

    Informationen zur Lagerung

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target

    CCRL1 (Chemokine (C-C Motif) Receptor-Like 1 (CCRL1))

    Andere Bezeichnung

    CCX-CKR

    Hintergrund

    Human CCX-CKR, also known as CCRL1, is a 40 kD, G-protein-coupled, seven transmembrane receptor. CCRL1 is a decoy receptor for CCL2, CCL8, CCL13, CCL19, CCL21 and CCL25 that regulates chemotaxis of lymphocytes and cancer cells. Chemokine binding by CCX-CKR causes its internalization, reducing levels of available chemokine, and thus regulating migration of lymphocytes and cancerous cells. CCX-CKR is expressed by stromal cells of skin-draining lymph nodes, thymic epithelial cells, and immature dendritic cells (DCs). A low CCX-CKR expression in tumor cells correlates with a poor survival rate of breast cancer patients.
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