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CCRL1 Antikörper (PE)

Dieser Anti-CCRL1 Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von CCRL1 in FACS. Geeignet für Human.
Produktnummer ABIN2662412

Kurzübersicht für CCRL1 Antikörper (PE) (ABIN2662412)

Target

Alle CCRL1 Antikörper anzeigen
CCRL1 (Chemokine (C-C Motif) Receptor-Like 1 (CCRL1))

Reaktivität

  • 19
  • 10
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 16
  • 2
  • 1
Maus

Klonalität

  • 18
  • 1
Monoklonal

Konjugat

  • 19
Dieser CCRL1 Antikörper ist konjugiert mit PE

Applikation

  • 14
  • 11
  • 8
  • 5
  • 5
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Klon

13E11
  • Aufreinigung

    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

    Isotyp

    IgG2b kappa
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Protect from prolonged exposure to light. Do not freeze.

    Lagerung

    4 °C

    Informationen zur Lagerung

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target

    CCRL1 (Chemokine (C-C Motif) Receptor-Like 1 (CCRL1))

    Andere Bezeichnung

    CCX-CKR

    Hintergrund

    Human CCX-CKR, also known as CCRL1, is a 40 kD, G-protein-coupled, seven transmembrane receptor. CCRL1 is a decoy receptor for CCL2, CCL8, CCL13, CCL19, CCL21 and CCL25 that regulates chemotaxis of lymphocytes and cancer cells. Chemokine binding by CCX-CKR causes its internalization, reducing levels of available chemokine, and thus regulating migration of lymphocytes and cancerous cells. CCX-CKR is expressed by stromal cells of skin-draining lymph nodes, thymic epithelial cells, and immature dendritic cells (DCs). A low CCX-CKR expression in tumor cells correlates with a poor survival rate of breast cancer patients.
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