CCR8 Antikörper (PE)

Produktnummer ABIN2662408

Der Maus Monoklonal Anti-CCR8-Antikörper wurde für FACS validiert. Er ist geeignet, CCR8 in Proben von Human zu detektieren.

Kurzübersicht für CCR8 Antikörper (PE) (ABIN2662408)

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CCR8 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: L263G8

Produktdetails anti-CCR8 Antikörper (PE)

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu CCR8

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Andere Bezeichnung: CCR8

Hintergrund: CCR8, also known as ChemR1, TER1, and CKR-L1, belongs to the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. CCR8 is expressed on some subsets of T cells, monocytes, macrophages, eosinophils, thymocytes, Langerhans cells, neurons, and vascular smooth muscle cells. Binding with its ligand CCL1, CCR8 plays a role in the regulation of monocyte chemotaxis and thymic cell apoptosis. It has been reported that CCR8 is also a receptor for CCL18. CCR8 is also believed to be an alternative coreceptor to CD4 for HIV-1 infection.