Der Pacific Blue-konjugierte Ratte Monoklonal anti-Ki-67 Antikörper (Klon 16A8) (ABIN2662184) detektiert spezifisch Ki-67 in FACS, IF, ELISA, IP und BR.
Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.
The nuclear protein Ki-67 was first identified by the monoclonal antibody Ki-67, which was generated by immunizing mice with nuclei of the L428 Hodgkin lymphoma cell line. Ki-67 protein plays an essential role in ribosomal RNA transcription and cell proliferation. Expression of Ki-67 occurs during G1, S, G2, and M phase, while in G0 phase the Ki-67 protein is not detectable. Ki-67 is strongly expressed in proliferating cells and has been reported as a prognostic marker in various tumors.
Aufreinigung
The antibody was purified by affinity chromatography and conjugated with Pacific Blue™ under optimal conditions. The solution is free of unconjugated Pacific Blue™.