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CD51 Antikörper (FITC)

ITGAV Reaktivität: Human FACS Wirt: Maus Monoclonal NKI-M9 FITC
Produktnummer ABIN2661768
  • Target Alle CD51 (ITGAV) Antikörper anzeigen
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    Reaktivität
    • 98
    • 55
    • 23
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 64
    • 35
    • 12
    Maus
    Klonalität
    • 56
    • 54
    Monoklonal
    Konjugat
    • 57
    • 10
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD51 Antikörper ist konjugiert mit FITC
    Applikation
    • 51
    • 48
    • 29
    • 26
    • 23
    • 15
    • 14
    • 14
    • 13
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Aufreinigung
    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
    Klon
    NKI-M9
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product ITGAV Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Protect from prolonged exposure to light. Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    Andere Bezeichnung
    CD51 (ITGAV Produkte)
    Hintergrund
    CD51 is a type I integral membrane glycoprotein, known as vitronectin receptor α chain, or integrin αV. It forms heterodimer with integrin β1 (CD29), β3 (CD61), β5, β6, or β8. CD51 contains two disulfide-linked subunits of 125 kD and 24 kD, and is expressed on endothelial cells, fibroblasts, macrophages, platelets, osteoclasts, neuroblastoma, melanoma, and hepatoma cells. Many extracellular matrix proteins with RGD-motifs are CD51 ligands. In association with its β chains, CD51 binds vitronectin, von Willebrand factor, fibronectin, thrombospondin, osteopontin, fibrinogen, and laminin. CD51, as an adhesion molecule, plays important roles in leukocytes homing and rolling, mediates bone absorption and angiogenesis.
    Pathways
    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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