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IL2 Receptor beta Antikörper (FITC)
IL2RB
Reaktivität: Maus
FACS
Wirt: Ratte
Monoclonal
TM-beta1
FITC
Produktnummer ABIN2661492
Produktdetails anti-IL2 Receptor beta Antikörper (FITC)
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Target
Alle IL2 Receptor beta (IL2RB) Antikörper anzeigen
IL2 Receptor beta (IL2RB)
(Interleukin 2 Receptor, beta (IL2RB))
Reaktivität
Alle Reaktivitäten für IL2 Receptor beta Antikörper
Maus
Wirt
Alle Wirte für IL2 Receptor beta Antikörper
Ratte
Klonalität
Alle Klonalitäten für IL2 Receptor beta Antikörper
Monoklonal
Konjugat
Alle Konjugate für IL2 Receptor beta Antikörper
Dieser IL2 Receptor beta Antikörper ist konjugiert mit FITC
Applikation
Alle Applikationen für IL2 Receptor beta Antikörper
Flow Cytometry (FACS)
Aufreinigung
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Klon
TM-beta1
Isotyp
IgG2b kappa
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Discover our top product IL2RB Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Protect from prolonged exposure to light. Do not freeze.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C.
Details zu IL2 Receptor beta
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Target
IL2 Receptor beta (IL2RB)
(Interleukin 2 Receptor, beta (IL2RB))
Andere Bezeichnung
CD122 (IL2RB Produkte )
Substanzklasse
Chemical
Hintergrund
CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit(CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The TM-β1 antibody does inhibit IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.
Pathways
JAK-STAT Signalweg , Growth Factor Binding
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