ITGA2 Antikörper (Biotin)

Produktnummer ABIN2661336

Der Ratte Monoklonal Anti-ITGA2-Antikörper wurde für FACS, WB, IHC, IP, BR und St validiert. Er ist geeignet, ITGA2 in Proben von Maus zu detektieren.

Kurzübersicht für ITGA2 Antikörper (Biotin) (ABIN2661336)

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser ITGA2 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Blocking Reagent (BR), Stimulation (St)

Klon: DX5

Produktdetails anti-ITGA2 Antikörper (Biotin)

Aufreinigung: The solution is free of unconjugated biotin.

Isotyp: IgM kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu ITGA2

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Andere Bezeichnung: CD49b

Hintergrund: DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex