Kurzübersicht für IL-12/IL-23 p40 Antikörper (Biotin) (ABIN2661204)
Target
IL-12/IL-23 p40
Reaktivität
Human
Wirt
Maus
Klonalität
Monoklonal
Konjugat
Dieser IL-12/IL-23 p40 Antikörper ist konjugiert mit Biotin
Applikation
Flow Cytometry (FACS)
Klon
C8-6
Kreuzreaktivität (Details)
IL-12/IL-23 p40 subunit (monomer, homodimer and heterodimer IL-12 p35/p40 or IL-23 p19/p40)
Produktmerkmale
The C8.6 antibody reacts with human IL-12 p40 subunit of the IL-12 p70 heterodimer and IL-23 p40 subunit of the IL-23 p19/p40, as well as p40 monomer and homodimer. The C8.6 antibody has been reported to strongly inhibit different biological activities of IL-12, (e.g., IFN-gamma induction, mitogenic effects on PHA blasts, and enhancement of NK cell-mediated cytotoxicity). The C8.6 antibody can neutralize the bioactivity of natural or recombinant IL-12.
Aufreinigung
The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.