Der Biotin-konjugierte Ratte Monoklonal anti-LAMP2 Antikörper (Klon M3-84) (ABIN2660906) detektiert spezifisch LAMP2 in FACS.
Dieser Antikörper reagiert spezifisch mit Proben aus Maus.
The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Do not freeze.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C.
Target
LAMP2
(Lysosomal-Associated Membrane Protein 2 (LAMP2))
Andere Bezeichnung
CD107b
Hintergrund
Mac-3 is a 110 kD type I membrane glycoprotein, also known as CD107b and LAMP-2. It is expressed on lysosomal membranes and the plasma membrane of macrophages and some myeloid cell lines. In the bone marrow, few cells display Mac-3 antigen on the surface, but a large proportion express Mac-3 in the cytoplasm. CD107b has been identified as a ligand for galaptin, an S-type lectin present in the extracellular matrix. Mac-3/CD107b is upregulated in some tumors and increased expression has been correlated with enhanced metastatic potential.