beta-2 Microglobulin Antikörper (Biotin)
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- Target Alle beta-2 Microglobulin (B2M) Antikörper anzeigen
- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser beta-2 Microglobulin Antikörper ist konjugiert mit Biotin
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Kreuzreaktivität
- Schwein
- Aufreinigung
- The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
- Klon
- 2M2
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product B2M Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from prolonged exposure to light. Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
- Andere Bezeichnung
- Beta2-Microglobulin (B2M Produkte)
- Hintergrund
- β2-microglobulin (β2M) is a 12 kD nonpolymorphic Ig like protein. It is a non-membrane-anchored glycoprotein and is noncovalently associated with 39-44 kD polymorphic heavy chains of MHC class I molecules to form HLA class I antigen complex. In association with HLA class I, β2M is expressed on all leukocytes, platelets, endothelial cells, and epithelial cells. β2M plays an essential role both in governing MHC class I molecules stability and in promoting antigen binding and presenting the antigen to CD3/TCR complex of CD8+ T cells.
- Pathways
- T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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