KIR2DL3 Antikörper (PerCP-Cy5.5)
Kurzübersicht für KIR2DL3 Antikörper (PerCP-Cy5.5) (ABIN2659978)
Target
Alle KIR2DL3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- The antibody was purified by affinity chromatography and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.
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Isotyp
- IgG2a kappa
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anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 42-140) antibody
KIR2DL3 Reaktivität: Human ELISA, ICC, IF (p), IF (cc), IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 22-245) antibodyKIR2DL3 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) antibodyKIR2DL3 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 22-245) antibodyKIR2DL3 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) antibodyKIR2DL3 Reaktivität: Human, Maus WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 22-342) antibodyKIR2DL3 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (Internal Region) antibodyKIR2DL3 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 1-341) antibodyKIR2DL3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 19-161) antibodyKIR2DL3 Reaktivität: Human WB, ELISA, IF, ICC Wirt: Maus Monoclonal 190IIC311 unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 19-161) antibodyKIR2DL3 Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 190IIC311 unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Protect from prolonged exposure to light. Do not freeze.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))
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Andere Bezeichnung
- CD158b
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Hintergrund
- CD158b is expressed on natural killer cells and a subset of T cells. It is a member of the immunoglobulin superfamily containing two immunoglobulin C2-type domains. Both variants and alternative isoforms of CD158b have been reported. The interaction of CD158b with specific HLA-C antigens on a target cell (HLA-Cw1, HLA-Cw3, HLA-Cw7 alleles, for example) inhibits cytotoxicity and prevents target cell lysis and death. The interactions between KIR and MHC class I are thought to be important in NK cell and T cell regulation following antigen stimulation. The absence of ligands for KIRs may lower the threshold for activation through activating receptors and increase inflammation and susceptibility to autoimmune disease.
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Pathways
- Cancer Immune Checkpoints
Target
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