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FAS Antikörper (PE-Cy7)
FAS
Reaktivität: Human
FACS
Wirt: Maus
Monoclonal
DX2
PE-Cy7
Produktnummer ABIN2659572
Produktdetails anti-FAS Antikörper (PE-Cy7)
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Target
Alle FAS Antikörper anzeigen
FAS
(TNF Receptor Superfamily, Member 6 (FAS))
Reaktivität
Alle Reaktivitäten für FAS Antikörper
Human
Wirt
Alle Wirte für FAS Antikörper
Maus
Klonalität
Alle Klonalitäten für FAS Antikörper
Monoklonal
Konjugat
Alle Konjugate für FAS Antikörper
Dieser FAS Antikörper ist konjugiert mit PE-Cy7
Applikation
Alle Applikationen für FAS Antikörper
Flow Cytometry (FACS)
Kreuzreaktivität
Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops), Pavian, Capuchin Monkey, Schimpanse, Marmoset, Saguinus oedipus, Cynomolgus, Pigtailed Macaque, Rhesusaffen, Sooty mangabey (Cercocebus atys), Green Monkey (Chlorocebus sabaeus)
Aufreinigung
The antibody was purified by affinity chromatography, and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
Klon
DX2
Isotyp
IgG1 kappa
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Discover our top product FAS Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Protect from prolonged exposure to light. Do not freeze.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C.
Details zu FAS
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Target
FAS
(TNF Receptor Superfamily, Member 6 (FAS))
Andere Bezeichnung
CD95 (FAS Produkte )
Hintergrund
CD95 is a 45 kD single chain type I glycoprotein also known as Fas, APO-1, and TNFRSF6. It is a member of the TNF receptor superfamily. CD95 is expressed on T and B lymphocytes, monocytes, neutrophils, and fibroblasts. CD95 expression is upregulated by activation. The extracellular region of CD95 binds to CD178 (Fas ligand). CD178 binding to CD95 induces apoptosis and has been shown to play a role in the maintenance of peripheral tolerance.
Pathways
p53 Signalweg , Apoptose , Production of Molecular Mediator of Immune Response , Positive Regulation of Endopeptidase Activity
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