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CD80 Antikörper (APC)

CD80 Reaktivität: Maus ICFC Wirt: Hamster Monoclonal 16-10A1 APC
Produktnummer ABIN2658718
  • Target Alle CD80 Antikörper anzeigen
    CD80
    Reaktivität
    • 139
    • 122
    • 44
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 88
    • 71
    • 25
    • 24
    • 23
    • 1
    • 1
    Hamster
    Klonalität
    • 153
    • 77
    • 2
    Monoklonal
    Konjugat
    • 90
    • 20
    • 19
    • 17
    • 14
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD80 Antikörper ist konjugiert mit APC
    Applikation
    • 141
    • 94
    • 70
    • 41
    • 34
    • 22
    • 14
    • 14
    • 13
    • 13
    • 12
    • 11
    • 11
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Intracellular Flow Cytometry (ICFC)
    Kreuzreaktivität
    Hund
    Aufreinigung
    The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
    Klon
    16-10A1
    Isotyp
    IgG
    Top Product
    Discover our top product CD80 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Protect from prolonged exposure to light. Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CD80
    Andere Bezeichnung
    CD80 (CD80 Produkte)
    Synonyme
    B7 antikoerper, B7-1 antikoerper, B7.1 antikoerper, BB1 antikoerper, CD28LG antikoerper, CD28LG1 antikoerper, LAB7 antikoerper, B71 antikoerper, Cd28l antikoerper, Ly-53 antikoerper, Ly53 antikoerper, MIC17 antikoerper, TSA1 antikoerper, CD80 molecule antikoerper, Cd80 molecule antikoerper, CD80 antigen antikoerper, CD80 antikoerper, Cd80 antikoerper
    Hintergrund
    CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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