Integrin alpha 1 Antikörper (APC)

Produktnummer ABIN2658243

Dieses Armenischer Hamster Monoklonal-Antikörper erkennt spezifisch Integrin alpha 1 in IHC und FACS. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Integrin alpha 1 Antikörper (APC) (ABIN2658243)

Target: Integrin alpha 1 (ITGA1)

Reaktivität: Maus

Wirt: Armenischer Hamster

Klonalität: Monoklonal

Konjugat: Dieser Integrin alpha 1 Antikörper ist konjugiert mit APC

Applikation: Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon: HMalpha1

Produktdetails anti-Integrin alpha 1 Antikörper (APC)

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu Integrin alpha 1

Target: Integrin alpha 1 (ITGA1)

Andere Bezeichnung: CD49a

Hintergrund: CD49a is a 1179 aa, type I transmembrane glycoprotein also known as α1 integrin, VLA-1 α chain, or integrin α1. It associates antibody v042010 with CD29 (β1 integrin) to form the VLA-1 complex, a collagen IV and alminin-1 receptor that is expressed on activated T cells, smooth muscle cells, endothelial cells, neuronal cells, fibroblasts, and mesenchymal cells. CD49a is an adhesion molecule and is involved in the regulation of leukocyte migration, T cell proliferation, and cytokine production.

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex