JAG1 Antikörper (APC)

Produktnummer ABIN2658199

Produktdetails anti-JAG1 Antikörper (APC)

Target: JAG1 (Jagged 1 (JAG1))

Reaktivität: Maus

Wirt: Armenischer Hamster

Klonalität: Monoklonal

Konjugat: Dieser JAG1 Antikörper ist konjugiert mit APC

Applikation: Cytometry by Time of Flight (CyTOF), ELISA (Capture)

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Klon: HMJ1-29

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu JAG1

Target: JAG1 (Jagged 1 (JAG1))

Andere Bezeichnung: CD339 (JAG1 Produkte)

Synonyme: AGS antikoerper, AHD antikoerper, AWS antikoerper, CD339 antikoerper, HJ1 antikoerper, JAGL1 antikoerper, ABE2 antikoerper, Gsfabe2 antikoerper, Htu antikoerper, Ozz antikoerper, Ser-1 antikoerper, JAG1 antikoerper, jag3 antikoerper, cb243 antikoerper, jag1 antikoerper, sb:cb243 antikoerper, serrateC antikoerper, jagged1 antikoerper, serrate antikoerper, serrate-1 antikoerper, x-serrate-1 antikoerper, jagged 1 antikoerper, jagged 1b antikoerper, jagged 1a antikoerper, jagged 1 L homeolog antikoerper, JAG1 antikoerper, Jag1 antikoerper, jag1 antikoerper, jag1b antikoerper, jag1a antikoerper, jag1.L antikoerper

Hintergrund: CD339, also known as Jagged 1, is a 135 kD type 1 transmembrane protein, with one DSL (Delta, Serrate, LagZ) domain, fifteen EGF-like domains, and one cysteine-rich region. Jagged 1 is expressed by many cell types including macrophages, subsets of dendritic cells, astrocytes, stromal, and epithelial cells. CD339 regulates cell fate decisions in various tissues, and has an important role in neurogenesis and development of the cardiovascular system. Studies suggest Jagged 1 is involved in Th2 polarization and Treg induction.

Pathways: Notch Signalweg, Stem Cell Maintenance