JAG1 Antikörper (Internal Region)

Produktnummer ABIN7218328

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch JAG1 in WB, IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für JAG1 Antikörper (Internal Region) (ABIN7218328)

Target: JAG1 (Jagged 1 (JAG1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JAG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-JAG1 Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: Rabbit Anti-Jagged1 Polyclonal Antibody

Spezifität: Jagged1 Polyclonal Antibody detects endogenous levels of Jagged1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Jagged1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:50-200,WB 1:500-1:2000,IHC: 1:100-1:300,ELISA 1:20000,Not yet tested in other applications,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu JAG1

Target: JAG1 (Jagged 1 (JAG1))

Andere Bezeichnung: Jagged1

Hintergrund: JAG1, JAGL1, Protein jagged-1, Jagged1, hJ1, CD339The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Molekulargewicht: 140kD

Gen-ID: 182

UniProt: P78504

Pathways: Notch Signalweg, Stem Cell Maintenance