TLR3 Antikörper (APC)
-
- Target Alle TLR3 Antikörper anzeigen
- TLR3 (Toll-Like Receptor 3 (TLR3))
-
Reaktivität
- Maus
-
Wirt
- Ratte
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser TLR3 Antikörper ist konjugiert mit APC
-
Applikation
- Flow Cytometry (FACS)
- Aufreinigung
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
- Klon
- 11F8
- Isotyp
- IgG2a
- Top Product
- Discover our top product TLR3 Primärantikörper
-
anti-Toll-Like Receptor 3 (TLR3) (AA 404-532) antibody
TLR3 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 464-647) antibodyTLR3 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 801-905) antibodyTLR3 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 24-217) antibodyTLR3 Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 6F3G4 unconjugated
anti-Toll-Like Receptor 3 (TLR3) (C-Term) antibodyTLR3 Reaktivität: Human WB, IF, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 135-297) antibodyTLR3 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 55-70) antibodyTLR3 Reaktivität: Human, Affe, Ziege, Schaf WB, IHC, FACS, IP, IHC (p) Wirt: Maus Monoclonal 40C1285-6 unconjugated
anti-Toll-Like Receptor 3 (TLR3) antibodyTLR3 Reaktivität: Maus FACS, IF Wirt: Ratte Monoclonal 11F8 unconjugated
anti-Toll-Like Receptor 3 (TLR3) (C-Term) antibodyTLR3 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 750-800), (pTyr759) antibodyTLR3 Reaktivität: Human WB, IHC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 0.2 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from prolonged exposure to light. Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
-
- Target
- TLR3 (Toll-Like Receptor 3 (TLR3))
- Andere Bezeichnung
- CD283 (TLR3 Produkte)
- Hintergrund
- Toll-like receptor 3 (TLR3), also known as CD283, is type I transmembrane protein that belongs to the TLR family. It forms a large horseshoe shape that contacts a neighboring horseshoe, forming a dimer of two horseshoes. It is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. TLR3 is expressed selectively on the cytoplasmic membrane and intracellularly in dendritic cells. It is also highly expressed in the placenta, pancreas, heart, liver, lung, and muscle. TLR3 is a pattern recognition receptor that participates in innate immune response to microbial pathogens by recognizing polyinosine-polycytidylic acid (Poly(I:C)) and dsRNA. Ligand binding by TLR3 induces receptor dimerization which results in inducing NF-κB activation (via TRIF-linked RIP1/TLR3 interactions) and cytokine production. TLR3 has been shown to interact with a number of proteins including MYD88, TRAF6, TRIAD3, MAP3K7, and TAB2.
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
-
