NCR3 Antikörper (Alexa Fluor 647)

Produktnummer ABIN2657758

Produktdetails anti-NCR3 Antikörper (Alexa Fluor 647)

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NCR3 Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Flow Cytometry (FACS)

Produktmerkmale: The p30-15 monoclonal antibody recognizes CD337 also known as activating NK receptor NKp30 (NKp30), and natural cytotoxicity triggering receptor 3. NKp30 is a type I transmembrane protein, member of the natural cytotoxicity receptor family that contains one immunoglobulin-like domain. NKp30 has an apparent molecular weight of 30 kD and six isoforms are produced by alternative splicing. NKp30 is expressed on resting and activated NK cells. NKp30 enhances NK cell cytolysis of tumor cellts that are deficient in MHC class I molecules. NKp30 has been shown to associate with CD59 and TCRζ. The p30-15 antibody against human NKp30 has been shown to be useful for flow cytometry, stimulation of human NK cells via NKp30 in a redirected lysis assay, and blocking of NKp30 function in solution.

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

Klon: P30-15

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C

Details zu NCR3

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Andere Bezeichnung: CD337 (NCR3 Produkte)

Synonyme: MGC133750 antikoerper, 1C7 antikoerper, CD337 antikoerper, LY117 antikoerper, MALS antikoerper, NKp30 antikoerper, Nkp30 antikoerper, natural cytotoxicity triggering receptor 3 antikoerper, NCR3 antikoerper, Ncr3 antikoerper

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process