CD226 Antikörper (Alexa Fluor 647)
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- Target Alle CD226 Antikörper anzeigen
- CD226
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD226 Antikörper ist konjugiert mit Alexa Fluor 647
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Applikation
- Flow Cytometry (FACS)
- Aufreinigung
- The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
- Klon
- TX42-1
- Isotyp
- IgG2a
- Top Product
- Discover our top product CD226 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from prolonged exposure to light. Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C
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- Target
- CD226
- Andere Bezeichnung
- CD226 (CD226 Produkte)
- Synonyme
- CD226 antikoerper, cd226 antikoerper, zgc:158817 antikoerper, BC051526 antikoerper, DNAM-1 antikoerper, DNAM1 antikoerper, Pta1 antikoerper, TLiSA1 antikoerper, PTA1 antikoerper, CD226 molecule antikoerper, CD226 antigen antikoerper, CD226 antikoerper, cd226 antikoerper, Cd226 antikoerper
- Hintergrund
- Mouse CD226 (DNAM-1) is a 65 kd glycoprotein of a member of Ig super-family adhesion molecule containing 2 immunoglobulin-like domains. It is associated with leukocyte function associated antigen-1 (LFA-1) involving in TCR-mediated signal transduction for T cell proliferation and differentiation. CD226 is also involved in NK cell and T cell mediated cytotoxicity against certain tumors. CD226 (DNAM-1) is constitutively expressed on naive CD8+ and CD4+ T cells, macrophages, and NK cells. It was reported that CD226 expression is up-regulated on Th1 cells, but down-regulated on Th2 and Th0 cells. CD155 and CD112 are the ligands for CD226.
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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