IL17F Antikörper (Alexa Fluor 488)

Produktnummer ABIN2657540

Der Alexa Fluor 488-konjugierte Ziege Polyklonal anti-IL17F Antikörper (Klon Poly5166) (ABIN2657540) detektiert spezifisch IL17F in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IL17F Antikörper (Alexa Fluor 488) (ABIN2657540)

Target: IL17F (Interleukin 17F (IL17F))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser IL17F Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB)

Klon: Poly5166

Produktdetails anti-IL17F Antikörper (Alexa Fluor 488)

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C

Details zu IL17F

Target: IL17F (Interleukin 17F (IL17F))

Andere Bezeichnung: IL-17F

Hintergrund: IL-17F is part of the IL-17 cytokine family which consists of at least seven structurally related proteins (IL-17A, B, C, D, E, F, and A/F). IL-17F homodimer adopts a cysteine knot motif formed through the interactions of four cysteines, one of which is responsible for inter-chain bonding. IL-17F is most closely related to IL-17A, sharing 50 % amino acid sequence homology. It is expressed by Th17 cells, along with IL-17A homodimer and IL-17A/F heterodimer. IL-17F has been shown to inhibit endothelial cell angiogenesis and induce increased production of IL-2, TGF-β, and MCP-1, playing a critical role in the regulation of inflammatory reactions.

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity