ITGA2 Antikörper (Alexa Fluor 488)
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- Target Alle ITGA2 Antikörper anzeigen
- ITGA2 (Integrin alpha 2 (ITGA2))
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Reaktivität
- Maus
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Wirt
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Hamster
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Klonalität
- Monoklonal
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Konjugat
- Dieser ITGA2 Antikörper ist konjugiert mit Alexa Fluor 488
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Applikation
- Flow Cytometry (FACS)
- Aufreinigung
- The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.
- Klon
- HMalpha2
- Isotyp
- IgG
- Top Product
- Discover our top product ITGA2 Primärantikörper
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anti-Integrin alpha 2 (ITGA2) (AA 30-119) antibody
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anti-Integrin alpha 2 (ITGA2) (AA 170-361) antibodyITGA2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
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anti-Integrin alpha 2 (ITGA2) (AA 74-277) antibodyITGA2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin alpha 2 (ITGA2) (AA 188-365) antibodyITGA2 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from prolonged exposure to light. Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C
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- Target
- ITGA2 (Integrin alpha 2 (ITGA2))
- Andere Bezeichnung
- CD49b (ITGA2 Produkte)
- Hintergrund
- CD49b is a 150 kD glycoprotein, also known as α2 integrin, VLA-2 α chain, Integrin α2 chain, and HMα2. It is a member of the integrin family, expressed on NK cells, a subset of splenic CD4+ T cells, NK-T cells, intestinal intraepithelial and lamina propria lymphocytes, epithelial cells, and platelets. By associating with CD29 (integrin β1 subunit), CD49b forms the VLA-2 (integrin α2β1 ) complex. It plays a critical role in both adhesion and lymphocyte activation. The primary ligands for CD49b are collagen, laminin, and fibronectin. The HMα2 antibody has been shown to be useful for partially blocking CD49b mediated interactions with collagen. Additionally, this antibody blocks staining of splenic NK cells by the monoclonal antibody DX5.
- Pathways
- CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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