CD45RA Antikörper (Alexa Fluor 488)

Produktnummer ABIN2657445

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD45RA in FACS und ICFC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD45RA Antikörper (Alexa Fluor 488) (ABIN2657445)

Target: CD45RA

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD45RA Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Klon: HI100

Produktdetails anti-CD45RA Antikörper (Alexa Fluor 488)

Kreuzreaktivität: Schimpanse

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C

Details zu CD45RA

Target: CD45RA

Andere Bezeichnung: CD45RA

Hintergrund: CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naive T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.