NK-1.1/CD161c Antikörper (Alexa Fluor 700)

Produktnummer ABIN2657284

Der Maus Monoklonal Anti-NK-1.1/CD161c-Antikörper wurde für FACS validiert. Er ist geeignet, NK-1.1/CD161c in Proben von Maus zu detektieren.

Kurzübersicht für NK-1.1/CD161c Antikörper (Alexa Fluor 700) (ABIN2657284)

Target: NK-1.1/CD161c (NK-1.1)

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NK-1.1/CD161c Antikörper ist konjugiert mit Alexa Fluor 700

Applikation: Flow Cytometry (FACS)

Klon: PK136

Produktdetails anti-NK-1.1/CD161c Antikörper (Alexa Fluor 700)

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 700 under optimal conditions.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C

Details zu NK-1.1/CD161c

Target: NK-1.1/CD161c (NK-1.1)

Hintergrund: NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.