Cadherin 5 Antikörper (Alexa Fluor 647)

Produktnummer ABIN2657129

Dieses Anti-Cadherin 5-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Cadherin 5 in IP, FACS, BR und CoSt. Geeignet für Human.

Kurzübersicht für Cadherin 5 Antikörper (Alexa Fluor 647) (ABIN2657129)

Target: Cadherin 5 (CDH5)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cadherin 5 Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Immunoprecipitation (IP), Flow Cytometry (FACS), Blocking Reagent (BR), Co-Stimulation (CoSt)

Klon: BV9

Produktdetails anti-Cadherin 5 Antikörper (Alexa Fluor 647)

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C

Details zu Cadherin 5

Target: Cadherin 5 (CDH5)

Andere Bezeichnung: CD144

Hintergrund: CD144, also known as VE-cadherin and cadherin-5, is a 140 kD glycoprotein which is composed of five extracellular cadherin repeats and a highly conserved cytoplasmic tail region. It is a calcium-dependent transmembrane cell-cell adhesion molecule localized at the intercellular boundaries of endothelial cells, hematopoietic stem cells, and perineurial cells. It functions as a classic cadherin by mediating homophilic adhesion and functions as a plasma membrane attachment site for the cytoskeleton. CD144 is thought to play a role in vascular development, permeability, and remodeling.

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2