Der Alexa Fluor 488-konjugierte Ratte Monoklonal anti-Ki-67 Antikörper (Klon 16A8) (ABIN2657090) detektiert spezifisch Ki-67 in FACS.
Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.
The nuclear protein Ki-67 was first identified by the monoclonal antibody Ki-67, which was generated by immunizing mice with nuclei of the L428 Hodgkin lymphoma cell line. Ki-67 protein plays an essential role in ribosomal RNA transcription and cell proliferation. Expression of Ki-67 occurs during G1, S, G2, and M phase, while in G0 phase the Ki-67 protein is not detectable. Ki-67 is strongly expressed in proliferating cells and has been reported as a prognostic marker in various tumors.
Aufreinigung
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.