Dieser beta-2 Microglobulin Antikörper ist konjugiert mit APC
Applikation
Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)
Kreuzreaktivität
Schwein
Aufreinigung
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
β2-microglobulin (β2M) is a 12 kD nonpolymorphic Ig like protein. It is a non-membrane-anchored glycoprotein and is noncovalently associated with 39-44 kD polymorphic heavy chains of MHC class I molecules to form HLA class I antigen complex. In association with HLA class I, β2M is expressed on all leukocytes, platelets, endothelial cells and epithelial cells. β2M plays an essential role both in governing MHC class I molecules' stability and in promoting antigen binding and presenting the antigen to CD3/TCR complex of CD8+ T cells.