beta-2 Microglobulin Antikörper (APC)

Produktnummer ABIN2656877

Dieses Anti-beta-2 Microglobulin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von beta-2 Microglobulin in FACS und CyTOF. Geeignet für Human.

Kurzübersicht für beta-2 Microglobulin Antikörper (APC) (ABIN2656877)

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser beta-2 Microglobulin Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)

Klon: 2M2

Produktdetails anti-beta-2 Microglobulin Antikörper (APC)

Kreuzreaktivität: Schwein

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C

Details zu beta-2 Microglobulin

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Andere Bezeichnung: Beta2-Microglobulin

Hintergrund: β2-microglobulin (β2M) is a 12 kD nonpolymorphic Ig like protein. It is a non-membrane-anchored glycoprotein and is noncovalently associated with 39-44 kD polymorphic heavy chains of MHC class I molecules to form HLA class I antigen complex. In association with HLA class I, β2M is expressed on all leukocytes, platelets, endothelial cells and epithelial cells. β2M plays an essential role both in governing MHC class I molecules' stability and in promoting antigen binding and presenting the antigen to CD3/TCR complex of CD8+ T cells.

Pathways: T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process