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HDAC6 Antikörper
HDAC6
Reaktivität: Human, Maus, Ratte
WB, IF, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-HDAC6 Antikörper
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Target
Alle HDAC6 Antikörper anzeigen
HDAC6
(Histone Deacetylase 6 (HDAC6))
Reaktivität
Alle Reaktivitäten für HDAC6 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für HDAC6 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für HDAC6 Antikörper
Polyklonal
Konjugat
Alle Konjugate für HDAC6 Antikörper
Dieser HDAC6 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für HDAC6 Antikörper
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
This antibody detects endogenous levels of HDAC6 protein. (region surrounding His1203)
Kreuzreaktivität (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Aufreinigung
Affinity Chromatography using epitope-specific immunogen.
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Discover our top product HDAC6 Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
ELISA: 1/5000approx. 1/20000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu HDAC6
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Target
HDAC6
(Histone Deacetylase 6 (HDAC6))
Andere Bezeichnung
HDAC6 (HDAC6 Produkte )
Synonyme
HD6 antikoerper, Hd6 antikoerper, Hdac5 antikoerper, Sfc6 antikoerper, mHDA2 antikoerper, CG6170 antikoerper, DHDAC2 antikoerper, DmHDAC2 antikoerper, Dmel\\CG6170 antikoerper, HDAC antikoerper, HDAC2 antikoerper, dHDAC2 antikoerper, dHDAC6 antikoerper, dmHDA404 antikoerper, hdac6 antikoerper, MGC53140 antikoerper, wu:fc31d02 antikoerper, dsim_GLEANR_17355 antikoerper, DsimGD17207 antikoerper, GD17207 antikoerper, HDAC6 antikoerper, ATHDA6 antikoerper, AXE1 antikoerper, HISTONE DEACETYLASE 6 antikoerper, MDC12.7 antikoerper, MDC12_7 antikoerper, RNA-MEDIATED TRANSCRIPTIONAL SILENCING 1 antikoerper, RPD3B antikoerper, RTS1 antikoerper, SIL1 antikoerper, histone deacetylase 6 antikoerper, histone deacetylase 6 antikoerper, Histone deacetylase 6 antikoerper, histone deacetylase 6 L homeolog antikoerper, GD17207 gene product from transcript GD17207-RB antikoerper, Histone DeAcetylase antikoerper, HDAC6 antikoerper, Hdac6 antikoerper, hdac6.L antikoerper, hdac6 antikoerper, Dsim\HDAC6 antikoerper, PTRG_03035 antikoerper, HDA6 antikoerper, hda-6 antikoerper
Hintergrund
HDAC6 is a member of the class II mammalian histone deacetylases. Human HDAC6 is composed of 1215 amino acid residues. It possesses two separate putative catalytic domains. Both catalytic domains are fully functional HDACs and contribute independently to the overall activity of HDAC6 protein. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. The expression of HDAC6 is tightly linked to the state of cell differentiation. HDAC6 may participate in coordinating expression of a group of genes involved in the remodelling of chromatin during cell differentiation.Synonyms: HD6, Histone deacetylase 6, JM21, KIAA0901
Molekulargewicht
approx. 131, 160 kDa
Gen-ID
10013
NCBI Accession
NP_006035
UniProt
Q9UBN7
Pathways
Intracellular Steroid Hormone Receptor Signaling Pathway , Regulation of Intracellular Steroid Hormone Receptor Signaling
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