DP1 Antikörper

Produktnummer ABIN265387

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DP1 in WB, IF, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für DP1 Antikörper (ABIN265387)

Target: DP1 (TFDP1) (Transcription Factor Dp-1 (TFDP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-DP1 Antikörper

Spezifität: This antibody detects endogenous levels of DP-1/TFDP1 protein (region surrounding Val393).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 5000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu DP1

Target: DP1 (TFDP1) (Transcription Factor Dp-1 (TFDP1))

Andere Bezeichnung: TFDP1

Hintergrund: The human retinoblastoma gene product appears to play an important role in the negative egulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus-encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1 and S phases of the cell cycle. E2F-1 forms heterodimers with a second protein, designated DP-1, forming an Synonyms: DP1, DRTF1, DRTF1-polypeptide 1, E2F dimerization partner 1, Transcription factor Dp-1

Molekulargewicht: approx. 55 kDa

Gen-ID: 7027

NCBI Accession: NP_009042

UniProt: Q14186

Pathways: Zellzyklus, Mitotic G1-G1/S Phases